ChronoRecord Achievements

Validation Studies

Two validation studies were completed involving over 8600 days of data from 107 inpatients and outpatients with bipolar disorder. Concurrent validity was demonstrated between ChronoRecord and the Hamilton Depression Rating Scale (HAMD) and between ChronoRecord and the Young Mania Rating Scale (YMRS). See Validation for more information.

Awards

Recipient of the American Association for Technology in Psychiatry 2006 Gores Grant.

Translations

Translations of the ChronoRecord software into German, Spanish, Polish, and the conversion of the medication list for the UK, Australia and Canada are complete.

Publications

Bauer M, Glenn T, Alda M, Sagduyu K, Marsh W, Grof P, Munoz R, Baethge C, Lewitzka U, Pilhatsch M, Bauer R, Whybrow PC. Regularity in Daily Mood Stabilizer Dosage Taken by Patients with Bipolar Disorder. Pharmacopsychiatry (in press)

Bauer M, Glenn T, Alda M, Sagduyu K, Marsh W, Grof P, Munoz R, Severus E, Ritter P, Whybrow PC. Drug Treatment Patterns in Bipolar Disorder: Analysis of Long-Term Self-Reported Data. International Journal of Bipolar Disorders 2013, 1:5

Bauer M, Glenn T, Keil M, Bauer R, Marsh W, Grof P, Alda M, Sagduyu K. Murray G, Quiroz D, Baethge C, Whybrow PC. Brief Depressive Symptoms In Patients With Bipolar Disorder: Analysis Of Long-Term Self-Reported Data. Aust N Z J Psychiatry. 46:1068-1078

Bauer M, Glenn T, Alda M, Grof P, Sagduyu K, Bauer R, Lewitzka U, Whybrow PC. Comparison of Pre-Episode and Pre-Remission States Using Mood Ratings from Patients with Bipolar Disorder. Pharmacopsychiatry 2011: 44 Suppl 1:S49-53.

Bauer M, Glenn T, Rasgon N, Marsh W, Sagduyu K, Munoz R, Schmid R, Haack S, Whybrow PC. Association Between Median Family Income and Self-Reported Mood Symptoms in Bipolar Disorder. Compr Psychiatry 2011 52:17-25.

Bauer M, Glenn T, Rasgon N, Marsh W, Sagduyu K, Munoz R, Lewitska U, Schmid R, Whybrow PC. Association Between Age of Onset and Mood in Bipolar Disorder: Comparison of Subgroups Identified by Cluster Analysis and Clinical Observation. J Psychiatr Res 2010 44:1170-1175.

Bauer M, Glenn T, Rasgon N, Marsh W, Sagduyu K, Grof P, Alda M, Murray G, Munoz R, Quiroz D, Jabs B, Whybrow PC. Decreasing the Minimum Length Criterion for an Episode of Hypomania: Evaluation Using Self-reported Data from Patients with Bipolar Disorder. Eur Arch Psychiatry Clin Neurosci 2011 Jan 26.

Bauer M, Glenn T, Grof P, Marsh W, Sagduyu K, Alda M, Murray G, Lewitzka U, Schmid R, Haack S, Whybrow PC. The Association Between Concurrent Psychotropic Medications and Self-Reported Adherence with Taking a Mood Stabilizer in Bipolar Disorder. Hum Psychopharmacol 2009;25:47-54.

Bauer M, Glenn T, Grof P, Schmid R, Pfennig A, Whybrow PC. Subsyndromal Mood Symptoms: A Useful Concept for Maintenance Studies Of Bipolar Disorder? Psychopathology 2010;43:1-7.

Bauer M, Glenn T, Grof P, Rasgon NL, Marsh W, Sagduyu K, Alda M, Murray G, Quiroz D, Malliaris Y, Sasse J, Pilhatsch M, Whybrow PC. Relationship Among Latitude, Climate, Season and Self-Reported Mood in Bipolar Disorder. J Affect Disord 2009;116:152-157.

Bauer M, Glenn T, Grof P, Rasgon NL, Marsh W, Sagduyu K, Alda M, Lewitzka U, Sasse J, Kozuch-Krolik E, Whybrow PC. Frequency of Subsyndromal Symptoms and Employment Status in Patients with Bipolar Disorder. Soc Psychiatry Psychiatr Epidemiol 2009;44:515-522.

Bauer M, Glenn T, Grof P, Rasgon N, Alda M, Marsh W, Sagduyu K, Schmid R, Adli M, Whybrow PC. Comparison of Sleep/Wake Parameters for Self-Monitoring Bipolar Disorder. J Affect Disord 2009;116:170-175.

Bauer M, Glenn T, Whybrow PC, Grof P, Rasgon N, Alda M, Marsh W, Sagduyu K, Schmid R, Adli M. Changes in self-reported sleep duration predict mood changes in bipolar disorder. Psychol Med 2008;38:1069-71.

Bauer M, Glenn T, Grof P, Rasgon NL, Marsh W, Sagduyu K, Alda M, Lewitzka U, Schmid R, Whybrow PC. Relationship between adjunctive medications for anxiety and time spent ill in patients with bipolar disorder. International Journal of Psychiatry in Clinical Practice 2009;13:70-77.

Bauer M, Kozuch E, Glenn T, Grof P, Gutzmann C, Kiermeir J, Neuhaus K, Rasgon N, Ricken R, Sasse J, Schmid R, Whybrow PC. Die elektronische Erfassung des longitudinalen Verlaufs bipolarer Störungen (The electronic assessment of the longitudinal course of bipolar disorder with ChronoRecord software) Nervenheilkunde 2008;27:165–172.

Bauer M, Glenn T, Grof P, Pfennig A, Rasgon NL, Marsh W, Muñoz RA, Sagduyu K, Alda M, Quiroz D, Sasse J, Whybrow PC. Self-Reported Data from Patients with Bipolar Disorder: Frequency of Brief Depression. J Affect Disord 2007;101:227-233.

Bauer M, Wilson T, Neuhaus K, Sasse J, Pfennig A, Lewitzka U, Grof P, Glenn T, Rasgon N, Bschor T, Whybrow PC. Self-reporting Software for Bipolar Disorder: Validation of ChronoRecord by Patients with Mania. Psychiatry Res 2008;159:359-366.

Bauer M, Grof P, Rasgon NL, Marsh W, Muñoz RA, Sagduyu K, Alda M, Quiroz D, Glenn T, Baethge C, Whybrow PC. Self-Reported Data from Patients with Bipolar Disorder: Impact on Minimum Episode Length for Hypomania. J Affect Disord 2006;96:101-5.

Glenn T, Whybrow PC, Rasgon N, Grof P, Alda M, Baethge C, Bauer M. Approximate Entropy of Self-Reported Mood Prior to Episodes. Bipolar Disord 2006;8:424-9.

Bauer M, Grof P, Rasgon N, Bschor T, Glenn T, Whybrow PC. Temporal Relation Between Sleep and Mood in Patients with Bipolar Disorder. Bipolar Disord 2006;8:160-167.

Bauer M, Rasgon N, Grof P, Glenn T, Lapp M, Marsh W, Muñoz R, Suwalska A, Baethge C, Bschor T, Alda M, Whybrow PC. Do Antidepressants Influence Mood Patterns? A Naturalistic Study in Bipolar Disorder. Eur Psychiatry 2006;21:262-269.

Bauer M, Grof P, Rasgon N, Glenn T, Alda M, Priebe S, Whybrow PC. Mood Charting and Technology: New Approach to Monitoring Patients with Mood Disorders. Current Psychiatry Reviews 2006;2:423-429.

Bauer M, Rasgon N, Grof P, Gyulai L, Glenn T, Whybrow PC. Does The Use Of An Automated Tool For Self-Reporting Mood By Patients With Bipolar Disorder Bias The Collected Data? MedGenMed 2005;7(3).

Adli M, Whybrow PC, Grof P, Rasgon N, Gyulai L, Glenn T, Bauer M. Use Of Polypharmacy And Self-Reported Mood In Outpatients With Bipolar Disorder. International Journal of Psychiatry in Clinical Practice 2005;9:251-6.

Bauer M, Rasgon N, Grof P, Altshuler L, Gyulai L, Lapp M, Glenn T, Whybrow PC. Mood Changes Related To Antidepressants: A Longitudinal Study Of Patients With Bipolar Disorder In A Naturalistic Setting. Psychiatry Res 2005;133:73-80.

Bauer M, Grof P, Rasgon N, Sasse J, Glenn T, Neuhaus K, Gutzmann C, Whybrow PC. New Technology for Longitudinal Studies of Patients with Bipolar Disorder. Clinical Approaches in Bipolar Disorders 2005;4:4-10.

Rasgon NL, Bauer M, Grof P, Gyulai L, Elman S, Glenn T, Whybrow PC. Sex-Specific Self-Reported Mood Changes By Patients with Bipolar Disorder. J Psychiatr Res 2005;39:77-83.

Bauer M, Grof P, Gyulai L, Rasgon N, Glenn T, Whybrow PC. Using Technology to Improve Longitudinal Studies: Self-Reporting in Bipolar Disorder Bipolar Disord 2004;6:67-74.

Becker OV, Rasgon NL, Marsh WK, Glenn T, Ketter TA. Lamotrigine Therapy In Treatment-Resistant Menstrually-Related Rapid Cycling Bipolar Disorder: A Case Report. Bipolar Disord. 2004;6:435-9.

Whybrow PC, Grof P, Gyulai L, Rasgon N, Glenn T, Bauer M. The Electronic Assessment of the Longitudinal Course of Bipolar Disorder: The ChronoRecord Software. Pharmacopsychiatry 2003;36 (Suppl 3):S244-S249.

Rasgon NL, Bauer M, Glenn T, Elman S, Whybrow PC. Menstrual Cycle Related Mood Changes In Women With Bipolar Disorder. Bipolar Disord 2003;5:48-52.

Presentations

"Association of Age of Onset and Mood in Bipolar Disorder: Comparing Subgroups Identified by Cluster Analysis and Clinical Observation" poster presentation at APA, New Orleans, May 2010.

"The Association Between Concurrent Psychotropic Medications and Self-Reported Adherence with Taking a Mood Stabilizer" poster presentation at ISBD, Sao Paulo, Brazil, March 2010.

"Latitude, Climate, Season and Self-Reported Mood in Bipolar Disorder" poster presentation at APA, San Francisco, May 2009.

"Automated Patient Mood Charting" presentation at the American Association for Technology in Psychiatry meeting, Washington, DC, May 2008.

"Employment Status and Subsyndromal Symptoms in Bipolar Disorder" and "Changes in Sleep Duration and Changes in Mood in Bipolar Disorder" poster presentations at APA, Washington, DC, 2008.

"Day to Day Variability in Bipolar Disorder" workshop presentation at APA, San Diego, May 2007

"Update on ChronoRecord Association Activities" presentation at the American Association for Technology in Psychiatry meeting, San Diego, May 2007.

"Self-Reported Depression and Minimum Length of Depressive Episodes in Bipolar Disorder" and "Approximate Entropy of Self-Reported Mood Prior to Episodes in Patients With Bipolar Disorder" poster presentations at Seventh International Bipolar Conference in Pittsburgh, Jun 2007.

"Evaluating New Technology Innovations" workshop presentation at AMIA, Washington, DC, Nov 2006.

"A New Program of Group Psychoeducation and Computer Based Daily Charting with ChronoRecord in Bipolar Disorder" poster presentation at the 5th European Stanley Conference on Bipolar Disorder, Barcelona, Spain, Oct 2006.

"Improving Symptom Monitoring - Using Technology To Explore the Course of Bipolar Disorder" workshop presentation at ISBD, Edinburgh, Scotland, Aug 2006.

"Electronic Assessment of the Longitudinal Course of Bipolar Disorders" presentation at the European Network for Ambulatory Assessment. Symposium: Ambulatory Assessment in Psychiatry and Clinical Psychology. Zentralinstitut für Seelische Gesundheit, Mannheim, Germany, Aug 2006.

"Computer-Based Patient-Centered Monitoring: An Emerging Technology?" workshop presentation at AMIA, Washington, DC, Oct 2005.

"Validation of ChronoRecord Self-Reporting Software By Inpatients with Mania" poster presentation at APA, Atlanta, GA, May 2005.

"Temporal Relation Between Sleep and Mood in Bipolar Disorder" poster presentation at APA, Atlanta, GA, May 2005.

"ChronoRecord Update 2004" presentation at the IGSLI Conference, Vienna, Austria, Oct 2004.

"Using Software to Imporve Longitudinal Studies: Self-Reporting with ChronoRecord in Bipolar Disorder" poster presentation at the European Stanley Bipolar Conference, Aarhus, Denmark, Sep 2004.

"Sleep and Mood in Patients Treated for Bipolar Disorder: A Time Series Approach" poster presentation at NCDEU, Phoenix, Jun 2004.

Participation in "The Office of the Future: Technology in Psychiatry" workshop at APA, New York, May 2004.

"Does Automating Self-Reporting Bias the Data Collected from Patients with Bipolar Disorder" presentation at the American Association for Technology in Psychiatry meeting, New York, May 2004.

"Mood and Sleep in Patients Treated for Bipolar Disorder: A Time Series Approach" and "Mood and Menstrual Cycle in Bipolar Disorder: A Time Series Approach" poster presentation at APA, New York, May 2004.

"Using Technology to Improve Longitudinal Studies: Self-reporting in Bipolar Disorder Using ChronoRecord Computer Software", presentation at the European Workshop on Bipolar Disorder in Monastery Seeon, Germany, Mar 2004.

"Using Technology to Improve Longitudinal Studies of Mood Disorders" presentation at the Loyola University Medical Center, Symposium on Technology in Psychiatry, in Chicago, Nov 2003.

Data from final analysis of the validation study database presented at the German Bipolar Society meeting in Berlin, Sep 2003 and at the IGSLI Conference in 2003.

Poster presentation of data from the completed validation study at APA in May 2003, and at the 5^th International Bipolar Conference in Pittsburgh, Jun 2003.

"Using Technology to Improve Longitudinal Studies of Mood Disorders" presentation at the American Association for Technology in Psychiatry meeting, May 2003.

Poster presentation of preliminary data from the validation study at APA, NCDEU, the European Stanley Bipolar Conference and at IGSLI Conference in 2002.